compound 36j [PMID: 21536438]

Ligand id: 5755

Name: compound 36j [PMID: 21536438]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 116.59
Molecular weight 473.13
XLogP 3.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Xia Y, Chackalamannil S, Greenlee WJ, Jayne C, Neustadt B, Stamford A, Vaccaro H, Xu XL, Baker H, O'Neill K et al.. (2011)
Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes.
Bioorg. Med. Chem. Lett., 21 (11): 3290-6. [PMID:21536438]