compound R-(-)-5f [PMID: 22607879]

Ligand id: 5834

Name: compound R-(-)-5f [PMID: 22607879]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 58.64
Molecular weight 517.1
XLogP 7.89
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Cilibrizzi A, Schepetkin IA, Bartolucci G, Crocetti L, Dal Piaz V, Giovannoni MP, Graziano A, Kirpotina LN, Quinn MT, Vergelli C. (2012)
Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists.
Bioorg. Med. Chem., 20 (12): 3781-92. [PMID:22607879]