Ligand id: 5851

Name: BAY-73-1449

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 84.34
Molecular weight 425.17
XLogP 8.31
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Bexis S, McCormick PA, Docherty JR. (2008)
Vascular actions of the prostacyclin receptor antagonist BAY 73-1449 in the portal hypertensive rat.
Eur. J. Pharmacol., 590 (1-3): 322-6. [PMID:18603238]