Ligand id: 6078

Name: bepafant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 100.85
Molecular weight 467.12
XLogP 3.17
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Fern├índez-Gallardo S, Ortega MP, Priego JG, de Casa-Juana MF, Sunkel C, S├ínchez Crespo M. (1990)
Pharmacological actions of PCA 4248, a new platelet-activating factor receptor antagonist: in vivo studies.
J. Pharmacol. Exp. Ther., 255 (1): 34-9. [PMID:2170626]
2. Heuer HO, Casals-Stenzel J, Muacevic G, Weber KH. (1990)
Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor.
J. Pharmacol. Exp. Ther., 255 (3): 962-8. [PMID:2262914]