BIIL 260

Ligand id: 6154

Name: BIIL 260

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 88.56
Molecular weight 466.23
XLogP 9.01
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Birke FW, Meade CJ, Anderskewitz R, Speck GA, Jennewein HM. (2001)
In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist.
J. Pharmacol. Exp. Ther., 297 (1): 458-66. [PMID:11259574]
2. Díaz-González F, Alten RH, Bensen WG, Brown JP, Sibley JT, Dougados M, Bombardieri S, Durez P, Ortiz P, de-Miquel G et al.. (2007)
Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis.
Ann. Rheum. Dis., 66 (5): 628-32. [PMID:17170051]