Ligand id: 6238

Name: ADX88178

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 107.62
Molecular weight 272.08
XLogP 1.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Le Poul E, BolĂ©a C, Girard F, Poli S, Charvin D, Campo B, Bortoli J, Bessif A, Luo B, Koser AJ et al.. (2012)
A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease.
J. Pharmacol. Exp. Ther., 343 (1): 167-77. [PMID:22787118]