Ligand id: 6257

Name: cyPPTS

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 67.88
Molecular weight 414.12
XLogP 5.04
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. (2005)
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).
Psychopharmacology (Berl).179: 271- 283. [PMID:15717213]