cyPPTS

Ligand id: 6257

Name: cyPPTS

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 67.88
Molecular weight 414.12
XLogP 5.04
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. (2005)
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).
Psychopharmacology (Berl).179: 271- 283. [PMID:15717213]