Ligand id: 6262

Name: EC18

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 60.47
Molecular weight 496.29
XLogP 3.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Del Lungo M, Melchiorre M, Guandalini L, Sartiani L, Mugelli A, Koncz I, Szel T, Varro A, Romanelli MN, Cerbai E. (2012)
Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.
Br. J. Pharmacol., 166 (2): 602-16. [PMID:22091830]