compound 16m [PMID: 19931453]

Ligand id: 6429

Name: compound 16m [PMID: 19931453]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 58.12
Molecular weight 358.16
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Spanka C, Glatthar R, Desrayaud S, Fendt M, Orain D, Troxler T, Vranesic I. (2010)
Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity.
Bioorg. Med. Chem. Lett., 20 (1): 184-8. [PMID:19931453]