compound 10 [PMID: 15482906]

Ligand id: 6450

Name: compound 10 [PMID: 15482906]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 78.61
Molecular weight 334.1
XLogP 3.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Huang D, Poon SF, Chapman DF, Chung J, Cramer M, Reger TS, Roppe JR, Tehrani L, Cosford ND, Smith ND. (2004)
2-(2-[3-(pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl) pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.
Bioorg. Med. Chem. Lett., 14 (22): 5473-6. [PMID:15482906]