CAA0225

Ligand id: 6532

Name: CAA0225

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 14
Topological polar surface area 120.06
Molecular weight 487.21
XLogP 5.9
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

References
1. Takahashi K, Ueno T, Tanida I, Minematsu-Ikeguchi N, Murata M, Kominami E. (2009)
Characterization of CAA0225, a novel inhibitor specific for cathepsin L, as a probe for autophagic proteolysis.
Biol. Pharm. Bull.32 (3): 475-9. [PMID:19252298]