Ligand Id: 674
Ligand name FR173657

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 113.52
Molecular weight 591.14
XLogP 4.97
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
References
1. Aramori, I., Zenkoh, J., Morikawa, N., O'Donnell, N., Asano, M., Nakamura, K., Iwami, M., Kojo, H. and Notsu, Y. (1997)
Novel subtype-selective nonpeptide bradykinin receptor antagonists FR167344 and FR173657.
Mol Pharmacol, 51: 171-176. [PMID:9203620]
2. Rizzi, A; Gobeil, F; Calò, G; Inamura, N; Regoli, D. (1997)
FR 173657: a new, potent, nonpeptide kinin B2 receptor antagonist. An in vitro study.
Hypertension, 29 (4): 951-6. [PMID:9095082]