Compound class:
Peptide or derivative
Comment: Radiolabelled synthetic analogue of angiotensin II
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Feng YH, Noda K, Saad Y, Liu XP, Husain A, Karnik SS. (1995)
The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism. J Biol Chem, 270 (21): 12846-50. [PMID:7759541] |
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2. Tamura M, Wanaka Y, Landon EJ, Inagami T. (1999)
Intracellular sodium modulates the expression of angiotensin II subtype 2 receptor in PC12W cells. Hypertension, 33 (2): 626-32. [PMID:10024318] |
