compound 19a [PMID: 24359159]

Ligand id: 6977

Name: compound 19a [PMID: 24359159]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 109.23
Molecular weight 353.15
XLogP 1.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Su Q, Ioannidis S, Chuaqui C, Almeida L, Alimzhanov M, Bebernitz G, Bell K, Block M, Howard T, Huang S et al.. (2013)
Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors.
J. Med. Chem.,  [Epub ahead of print]. [PMID:24359159]