BMS pyrazole inhibitor 7f

Ligand id: 7030

Name: BMS pyrazole inhibitor 7f

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 152.99
Molecular weight 513.12
XLogP 4.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Huynh T, Chen Z, Pang S, Geng J, Bandiera T, Bindi S, Vianello P, Roletto F, Thieffine S, Galvani A et al.. (2009)
Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).
Bioorg. Med. Chem. Lett.19 (11): 2924-7. [PMID:19419866]