denileukin diftitox

Ligand id: 7044

Name: denileukin diftitox

References
1. Bacha P, Williams DP, Waters C, Williams JM, Murphy JR, Strom TB. (1988)
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
J. Exp. Med.167 (2): 612-22. [PMID:3126255]
2. Foley BT, Moehring JM, Moehring TJ. (1995)
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
J. Biol. Chem.270 (39): 23218-25. [PMID:7559470]
3. vanderSpek JC, Mindell JA, Finkelstein A, Murphy JR. (1993)
Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
J. Biol. Chem.268 (16): 12077-82. [PMID:8505330]