L-ornithine

Ligand id: 725

Name: L-ornithine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 89.34
Molecular weight 132.09
XLogP -3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Fiermonte G, Dolce V, David L, Santorelli FM, Dionisi-Vici C, Palmieri F, Walker JE. (2003)
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.
J. Biol. Chem., 278 (35): 32778-83. [PMID:12807890]
2. Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Brauner-Osborne H. (2005)
Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.
Mol Pharmacol., 67: 589-597. [PMID:15576628]