flutemetamol

Ligand id: 7342

Name: flutemetamol    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 73.39
Molecular weight 274.06
XLogP 2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Herholz K, Ebmeier K. (2011)
Clinical amyloid imaging in Alzheimer's disease.
Lancet Neurol10 (7): 667-70. [PMID:21683932]
2. Williams SC. (2013)
Alzheimer's imaging agents struggle to find a market outside trials.
Nat. Med.19 (12): 1551. [PMID:24309640]
3. Zha Z, Choi SR, Ploessl K, Lieberman BP, Qu W, Hefti F, Mintun M, Skovronsky D, Kung HF. (2011)
Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA).
J. Med. Chem.54 (23): 8085-98. [PMID:22011144]