Ligand id: 7420

Name: carfilzomib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 4
Rotatable bonds 24
Topological polar surface area 158.47
Molecular weight 719.43
XLogP 7.56
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

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Epoxomicin, a new antitumor agent of microbial origin.
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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma.
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