Ligand id: 7434

Name: budesonide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 93.06
Molecular weight 430.24
XLogP 1.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Habal FM, Huang VW. (2012)
Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient.
Aliment. Pharmacol. Ther., 35 (5): 501-15. [PMID:22221203]
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Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
J. Med. Chem., 60 (20): 8591-8605. [PMID:28937774]
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Management of Crohn's disease in adults.
Am. J. Gastroenterol., 104 (2): 465-83; quiz 464, 484. [PMID:19174807]
4. Millan DS, Ballard SA, Chunn S, Dybowski JA, Fulton CK, Glossop PA, Guillabert E, Hewson CA, Jones RM, Lamb DJ et al.. (2011)
Design and synthesis of long acting inhaled corticosteroids for the treatment of asthma.
Bioorg. Med. Chem. Lett., 21 (19): 5826-30. [PMID:21880489]