Ligand id: 7439

Name: lomitapide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 14
Topological polar surface area 61.44
Molecular weight 693.28
XLogP 13.87
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Robl JA, Sulsky R, Sun CQ, Simpkins LM, Wang T, Dickson Jr JK, Chen Y, Magnin DR, Taunk P, Slusarchyk WA et al.. (2001)
A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors.
J. Med. Chem., 44 (6): 851-6. [PMID:11300866]