compound 9 [PMID: 23788254]

Ligand id: 7492

Name: compound 9 [PMID: 23788254]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 104.32
Molecular weight 374.09
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Lee HY, Yang CR, Lai MJ, Huang HL, Hsieh YL, Liu YM, Yeh TK, Li YH, Mehndiratta S, Teng CM et al.. (2013)
1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.
Chembiochem, 14 (10): 1248-54. [PMID:23788254]