compound 36 [PMID: 24000170]

Ligand id: 7521

Name: compound 36 [PMID: 24000170]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 99.37
Molecular weight 470.12
XLogP 4.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Mirguet O, Lamotte Y, Chung CW, Bamborough P, DelannĂ©e D, Bouillot A, Gellibert F, Krysa G, Lewis A, Witherington J et al.. (2014)
Naphthyridines as novel BET family bromodomain inhibitors.
ChemMedChem, 9 (3): 580-9. [PMID:24000170]