tiludronic acid

Ligand id: 7604

Name: tiludronic acid

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 159.98
Molecular weight 317.93
XLogP -0.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Reginster JY, Jeugmans-Huynen AM, Albert A, Denis D, Deroisy R, Lecart MP, Fontaine MA, Collette J, Franchimont P. (1988)
Biological and clinical assessment of a new bisphosphonate, (chloro-4 phenyl) thiomethylene bisphosphonate, in the treatment of Paget's disease of bone.
Bone, 9 (6): 349-54. [PMID:3073800]
2. Tauro M, Laghezza A, Loiodice F, Agamennone M, Campestre C, Tortorella P. (2013)
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Bioorg. Med. Chem., 21 (21): 6456-65. [PMID:24071448]