prednicarbate

Ligand id: 7605

Name: prednicarbate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 116.2
Molecular weight 488.24
XLogP 2.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Gupta AK, Chow M. (2004)
A review of prednicarbate (Dermatop).
Skin Therapy Lett.9 (10): 5-6, 9. [PMID:15657633]
2. Kerscher MJ, Korting HC. (1992)
Topical glucocorticoids of the non-fluorinated double-ester type. Lack of atrophogenicity in normal skin as assessed by high-frequency ultrasound.
Acta Derm. Venereol.72 (3): 214-6. [PMID:1357864]
3. Korting HC, Vieluf D, Kerscher M. (1992)
0.25% prednicarbate cream and the corresponding vehicle induce less skin atrophy than 0.1% betamethasone-17-valerate cream and 0.05% clobetasol-17-propionate cream.
Eur. J. Clin. Pharmacol.42 (2): 159-61. [PMID:1618247]