lanicemine

Ligand id: 7681

Name: lanicemine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 38.91
Molecular weight 198.12
XLogP 1.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Cook D, Brown D, Alexander R, March R, Morgan P, Satterthwaite G, Pangalos MN. (2014)
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.
Nat Rev Drug Discov, 13 (6): 419-31. [PMID:24833294]
2. Monaghan DT, Larsen H. (1997)
NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology.
J. Pharmacol. Exp. Ther., 280 (2): 614-20. [PMID:9023271]
3. Zarate Jr CA, Mathews D, Ibrahim L, Chaves JF, Marquardt C, Ukoh I, Jolkovsky L, Brutsche NE, Smith MA, Luckenbaugh DA. (2013)
A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression.
Biol. Psychiatry, 74 (4): 257-64. [PMID:23206319]