Ligand id: 7753

Name: 4-arylphthalazin-1(2H)-3,4-Di-F

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 52.65
Molecular weight 516.23
XLogP 6.76
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Lim CJ, Kim SH, Lee BH, Oh KS, Yi KY. (2012)
4-arylphthalazin-1(2H)-one derivatives as potent antagonists of the melanin concentrating hormone receptor 1 (MCH-R1).
Bioorg. Med. Chem. Lett., 22 (1): 427-30. [PMID:22137790]