Ligand id: 7815

Name: dilmapimod

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 98.58
Molecular weight 456.14
XLogP 3.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Adams JL, Boehm JC, Hall R, Jin Q, Kasparec J, Silva DJ, Taggart JJ. 
Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compound for the treatment of CSBP/p38 kinase mediated diseases.
Patent number: EP1333833. Assignee: GlaxoSmithKline LLC. Priority date: 23/10/2000. Publication date: 23/10/2001.