Compound class:
Synthetic organic
Comment: ME-344 is an active metabolite of NV-128 [1], a novel flavonoid small molecule inhibitor of the mammalian target of rapamycin (mTOR).
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References |
1. Alvero AB, Montagna MK, Chen R, Kim KH, Kyungjin K, Visintin I, Fu HH, Brown D, Mor G. (2009)
NV-128, a novel isoflavone derivative, induces caspase-independent cell death through the Akt/mammalian target of rapamycin pathway. Cancer, 115 (14): 3204-16. [PMID:19472400] |
2. meipharma.
ME-344. Accessed on 20/11/2014. Modified on 20/11/2014. meipharma.com, http://www.meipharma.com/our-programs/me-344 |