BI-D1870

Ligand id: 8038

Name: BI-D1870

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 81.59
Molecular weight 391.18
XLogP 2.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Sapkota GP, Cummings L, Newell FS, Armstrong C, Bain J, Frodin M, Grauert M, Hoffmann M, Schnapp G, Steegmaier M et al.. (2007)
BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.
Biochem. J.401 (1): 29-38. [PMID:17040210]