CCT241533

Ligand id: 8044

Name: CCT241533

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 91.85
Molecular weight 442.2
XLogP 2.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Anderson VE, Walton MI, Eve PD, Boxall KJ, Antoni L, Caldwell JJ, Aherne W, Pearl LH, Oliver AW, Collins I et al.. (2011)
CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors.
Cancer Res.71 (2): 463-72. [PMID:21239475]