compound 1o [PMID: 24210504]

Ligand id: 8143

Name: compound 1o [PMID: 24210504]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 98.03
Molecular weight 429.23
XLogP 1.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Cho SY, Lee BH, Jung H, Yun CS, Ha JD, Kim HR, Chae CH, Lee JH, Seo HW, Oh KS. (2013)
Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors.
Bioorg. Med. Chem. Lett., 23 (24): 6711-6. [PMID:24210504]