compound 9b [PMID: 18986805]

Ligand id: 8160

Name: compound 9b [PMID: 18986805]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 84.73
Molecular weight 368.18
XLogP 3.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Jones CD, Andrews DM, Barker AJ, Blades K, Byth KF, Finlay MR, Geh C, Green CP, Johannsen M, Walker M et al.. (2008)
Imidazole pyrimidine amides as potent, orally bioavailable cyclin-dependent kinase inhibitors.
Bioorg. Med. Chem. Lett., 18 (24): 6486-9. [PMID:18986805]