compound 5b [PMID: 24900464]

Ligand id: 8171

Name: compound 5b [PMID: 24900464]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 110.9
Molecular weight 371.15
XLogP 1.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Dowling JE, Chuaqui C, Pontz TW, Lyne PD, Larsen NA, Block MH, Chen H, Su N, Wu A, Russell D et al.. (2012)
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.
ACS Med Chem Lett, 3 (4): 278-83. [PMID:24900464]