compound 11d [DOI: 10.1039/c0md00194e]

Ligand id: 8197

Name: compound 11d [DOI: 10.1039/c0md00194e]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 105.7
Molecular weight 423.18
XLogP 2.27
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Chen YT, Vojkovsky T, Fang X, Pocas JR, Grant W, Handy AMW, Schroter T, LoGrasso P, Bannister TD, Feng Y. (2011)
Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors.
Med Chem Commun, 2: 73-75.