compound 27 [PMID: 21123062]

Ligand id: 8210

Name: compound 27 [PMID: 21123062]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 99.25
Molecular weight 510.19
XLogP 5.31
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Weinberg LR, Albom MS, Angeles TS, Husten J, Lisko JG, McHugh RJ, Milkiewicz KL, Murthy S, Ott GR, Theroff JP et al.. (2011)
Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors.
Bioorg. Med. Chem. Lett., 21 (1): 164-7. [PMID:21123062]