compound 14k [PMID: 21982499]

Ligand id: 8214

Name: compound 14k [PMID: 21982499]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 79.38
Molecular weight 372.09
XLogP 4.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Pierre F, Stefan E, N├ędellec AS, Chevrel MC, Regan CF, Siddiqui-Jain A, Macalino D, Streiner N, Drygin D, Haddach M et al.. (2011)
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
Bioorg. Med. Chem. Lett., 21 (22): 6687-92. [PMID:21982499]