Ligand id: 8464

Name: droxinostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 58.56
Molecular weight 243.07
XLogP 1.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Wood TE, Dalili S, Simpson CD, Sukhai MA, Hurren R, Anyiwe K, Mao X, Suarez Saiz F, Gronda M, Eberhard Y et al.. (2010)
Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands.
Mol. Cancer Ther., 9 (1): 246-56. [PMID:20053768]