compound 2 [PMID: 24486398]

Ligand id: 8467

Name: compound 2 [PMID: 24486398]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 122.02
Molecular weight 446.18
XLogP 3.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Sakurai T, Davenport R, Stafford S, Grosse J, Ogawa K, Cameron J, Parton L, Sykes A, Mack S, Bousba S et al.. (2014)
Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing.
Eur. J. Pharmacol., 727: 1-7. [PMID:24486398]