AZ960

Ligand id: 8476

Name: AZ960

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 89.42
Molecular weight 354.14
XLogP 4.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Gozgit JM, Bebernitz G, Patil P, Ye M, Parmentier J, Wu J, Su N, Wang T, Ioannidis S, Davies A et al.. (2008)
Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2.
J. Biol. Chem.283 (47): 32334-43. [PMID:18775810]