AQ-RA 741

Ligand id: 8584

Name: AQ-RA 741

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 68.78
Molecular weight 463.29
XLogP 4.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Dörje F, Wess J, Lambrecht G, Tacke R, Mutschler E, Brann MR. (1991)
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
J. Pharmacol. Exp. Ther., 256 (2): 727-33. [PMID:1994002]
2. Gillberg PG, Sundquist S, Nilvebrant L. (1998)
Comparison of the in vitro and in vivo profiles of tolterodine with those of subtype-selective muscarinic receptor antagonists.
Eur. J. Pharmacol., 349 (2-3): 285-92. [PMID:9671109]