Ligand id: 8598

Name: Cy3B-telenzepine  

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 2
Rotatable bonds 18
Topological polar surface area 197.89
Molecular weight 1053.49
XLogP 8.38
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

1. Hern JA, Baig AH, Mashanov GI, Birdsall B, Corrie JE, Lazareno S, Molloy JE, Birdsall NJ. (2010)
Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules.
Proc. Natl. Acad. Sci. U.S.A., 107 (6): 2693-8. [PMID:20133736]
2. Nenasheva TA, Neary M, Mashanov GI, Birdsall NJ, Breckenridge RA, Molloy JE. (2013)
Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle.
J. Mol. Cell. Cardiol., 57: 129-36. [PMID:23357106]