compound 60 [PMID: 26155854]

Ligand id: 8641

Name: compound 60 [PMID: 26155854]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 88.17
Molecular weight 365.19
XLogP 1.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Demont EH, Chung CW, Furze RC, Grandi P, Michon AM, Wellaway C, Barrett N, Bridges AM, Craggs PD, Diallo H et al.. (2015)
Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.
J. Med. Chem., 58 (14): 5649-73. [PMID:26155854]