compound 8 [PMID: 17480064]

Ligand id: 8763

Name: compound 8 [PMID: 17480064]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 57.78
Molecular weight 213.09
XLogP 1.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Anderson DR, Meyers MJ, Vernier WF, Mahoney MW, Kurumbail RG, Caspers N, Poda GI, Schindler JF, Reitz DB, Mourey RJ. (2007)
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
J. Med. Chem.50 (11): 2647-54. [PMID:17480064]
2. Montagnoli A, Valsasina B, Croci V, Menichincheri M, Rainoldi S, Marchesi V, Tibolla M, Tenca P, Brotherton D, Albanese C et al.. (2008)
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
Nat. Chem. Biol.4 (6): 357-65. [PMID:18469809]