compound 8 [PMID: 17562362}

Ligand id: 8886

Name: compound 8 [PMID: 17562362}

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 141.26
Molecular weight 361.01
XLogP 0.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Deur C, Agrawal AK, Baum H, Booth J, Bove S, Brieland J, Bunker A, Connolly C, Cornicelli J, Dumin J et al.. (2007)
N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-D-aspartate receptor antagonists for the treatment of pain.
Bioorg. Med. Chem. Lett., 17 (16): 4599-603. [PMID:17562362]