compound 19 [PMID: 7707314]

Ligand id: 8892

Name: compound 19 [PMID: 7707314]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 92.62
Molecular weight 441.03
XLogP 2.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Uehling DE, Nanthakumar SS, Croom D, Emerson DL, Leitner PP, Luzzio MJ, McIntyre G, Morton B, Profeta S, Sisco J et al.. (1995)
Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs.
J. Med. Chem., 38 (7): 1106-18. [PMID:7707314]