Ligand id: 8959

Name: ensartinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 113.68
Molecular weight 546.13
XLogP 3.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Liang C. (2012)
Substituted pyridazine carboxamide compounds.
Patent number: WO2012048259. Assignee: Xcovery Holding Company, Llc. Priority date: 08/10/2010. Publication date: 12/04/2012.
2. Lovly CM, Heuckmann JM, de Stanchina E, Chen H, Thomas RK, Liang C, Pao W. (2011)
Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors.
Cancer Res., 71 (14): 4920-31. [PMID:21613408]