BMS-986123

Ligand id: 9159

Name: BMS-986123

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 103.76
Molecular weight 395.07
XLogP 2.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Burford N, Alt A. (2014)
Positive allosteric modulators and silent allosteric modulators of the opioid receptor.
Patent number: WO2014107344. Assignee: Bristol-Myers Squibb Company. Priority date: 04/01/2013. Publication date: 10/07/2014.
2. Burford NT, Clark MJ, Wehrman TS, Gerritz SW, Banks M, O'Connell J, Traynor JR, Alt A. (2013)
Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor.
Proc. Natl. Acad. Sci. U.S.A.110 (26): 10830-5. [PMID:23754417]