CX-6258

Ligand id: 9368

Name: CX-6258

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 65.79
Molecular weight 461.15
XLogP 4.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Haddach M, Michaux J, Schwaebe MK, Pierre F, O'Brien SE, Borsan C, Tran J, Raffaele N, Ravula S, Drygin D et al.. (2012)
Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor.
ACS Med Chem Lett3 (2): 135-9. [PMID:24900437]