Ligand id: 9448

Name: CMF-019

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 112.46
Molecular weight 455.22
XLogP 6.06
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP. (2016)
Cardiac action of the first G protein biased small molecule apelin agonist.
Biochem. Pharmacol., 116: 63-72. [PMID:27475715]